LOEWE Center for
Insect Biotechnology
& Bioresources

Miriam Kalsy


PhD student

Phone: +49 641 972-19299

Email: Miriam.Kalsy@ime.fraunhofer.de

Room: 2.42

Building: TIG


06/2018 Change of name from Heitmueller to Kalsy
seit 05/2016 PhD in the project of Dr. Krishnendu Mukherjee at Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Giessen (Germany)

Technical University Braunschweig, Germany
Master of Science Biology - Focus on microbiology and bioinformatics

Master Thesis :
„Investigation of factors affecting the survival of E. coli O157 : H7 in soil and colonization of Lactuca sativa

at Julius Kühn Institute, Braunschweig,
Institute for Epidemiology and Pathogen Diagnostic,
working group Bacteriology/Microbial ecology (Prof. Dr. Kornelia Smalla)

Technical University Braunschweig, Germany

Bachelor of Science Biology

Bachelor Thesis:
„Functional analysis of ResE and ResE mutant proteins in Bacillus subtilis

at Institute for Microbiology, Braunschweig (Dr. Elisabeth Härtig)

Research Interests

  • Humanpathogen E. coli - host interactions
  • Persistence and pathogenicity of humanpathogen E. coli
  • Influence of Pathogens on epigenetic mechanisms/regulation
  • Pathogen manipulation of complex host parameters (longevity, aging)
  • Development / discovery of new antimicrobial peptides


Kalsy M, Tonk M, Hardt M, et al. (2020) The insect antimicrobial peptide cecropin A disrupts uropathogenic Escherichia coli biofilms. npj Biofilms Microbiomes, 6 ((6)) https://doi.org/10.1038/s41522-020-0116-3
Mukherrjee K, Amsel D, Kalsy M, et al. (2020) MicroRNAs regulate innate immunity against uropathogenic and commensal-like Escherichia coli infections in the surrogate insect model Galleria mellonella. Scientific Reports , 10 https://doi.org/10.1038/s41598-020-59407-3
Heitmueller M, Billion A, Dobrindt U, Vilcinskas A, Mukherjee K (2017) Epigenetic mechanisms regulate innate immunity against uropathogenic and commensal-like Escherichia coli in the surrogate insect model Galleria mellonella Infection and Immunity,