LOEWE Center for
Insect Biotechnology
& Bioresources

Benedikt Leis

Dr. rer. nat.


Phone: +49 641 99-37780

Email: benedikt.leis@ime.fraunhofer.de

Room: 708

Building: HBR58


Since 2017

Postdoc at Sanofi-Fraunhofer Natural Product Center of Excellence

- high-throughput screening / new antimicrobial susceptibility tests

Postdoc, industrial biotechnology start-up project FasCiPlex, Freising

- automated screenings, enzymatic hydrolysis of cellulose

Doctoral thesis, Technical University of Munich (TUM)

- screening of industrially relevant hydrolases and functional (meta-)genomics

Master thesis at Institute of Food, Nutrition and Health, Swiss Federal Institute of Technology (ETH), Zurich, Switzerland

- phage endolysins and enzybiotics

Bachelor and Master of Science Biology, Technical University of Munich (TUM)

- microbiology, biotechnology, genetics

Research Interests

High-throughput screening strategies for the identification of antimicrobial active compounds, (meta)genomics and molecular biological tools for antibiotics discovery


Leis B, Held C, Bergkemper F, Dennemarck K, Steinbauer R, Reiter A, Mechelke M, Moerch M, Graubner S, Liebl W (2017) Comparative characterization of all cellulosomal cellulases from Clostridium thermocellum reveals high diversity in endoglucanase product formation essential for complex activity. Biotechnology for Biofuels, 10 , 240.
Leis B, Angelov A, Mientus M, Li H, Pham VTT, Lauinger B, Bongen P, Pietruszka J, Gonçalves LG, Santos H, Liebl W (2015) Identification of novel esterase-active enzymes from hot environments by use of the host bacterium Thermus thermophilus. Frontiers in Microbiology, 6 , 275.
Leis B, Heinze S, Angelov A, Pham VTT, Thürmer A, Jebbar M, Golyshin PN, Streit WR, Daniel R, Liebl W (2015) Functional screening of hydrolytic activities reveals an extremely thermostable cellulase from a deep-sea archaeon. Frontiers in Bioengineering and Biotechnology, 3 , 95.
Li H, Angelov A, Pham VTT, Leis B, Liebl W (2015) Characterization of chromosomal and megaplasmid partitioning loci in Thermus thermophilus HB27. BMC Genomics, 16 (1) , 317.
Leis B, Angelov A, Li H, Liebl W (2014) Genetic analysis of lipolytic activities in Thermus thermophilus HB27. Journal of Biotechnology, 191 , 150-157.
Angelov A, Li H, Geissler A, Leis B, Liebl W (2013) Toxicity of indoxyl derivative accumulation in bacteria and its use as a new counterselection principle. Systematic and Applied Microbiology, 36 (8) , 585-592.
Leis B, Angelov A, Liebl W (2013) Screening and expression of genes from metagenomes. 83, , 1-68.