LOEWE Zentrum für
Insektenbiotechnologie
& Bioressourcen

Jens Glaeser

PD Dr. rer. nat.

Gruppenleiter

Telefon: +49 641 99-37761

E-Mail: jens.glaeser@ime.fraunhofer.de

Raum: 775b

Gebäude: HBR58

Kurzlebenslauf

seit 04/2014

Gruppenleiter, Sanofi-Fraunhofer Natural Products Centre of Excellence

Innovative Kultivierungsmethoden und Metagenomik

Fraunhofer IME Bioressourcen
2013–2014 Lehrkraft für Mikrobiologie und Molekularbiologie
Universität Siegen
2012–2013 Vertretung der Professur für Mikrobiologie
Institut für Mikrobiologie und Molekularbiologie, Justus Liebig Universität Gießen
2012 Venia legendii und Ernennung zum Privatdozent für Mikrobiologie und Molekularbiologie
Fachbereich 08: Chemie und Biologie, Justus Liebig Universität Gießen
2006–2012 Habilitation
“Effects of photosensitized singlet oxygen formation on bacteria”
2002–2006 Wissenschaftlicher Mitarbeiter und Postdoc in der Molekulargenetik
Institut für Mikrobiologie und Molekularbiologie, Justus Liebig Universität Gießen (Prof. G. Klug)
2004 Dissertation: Dr. rer. nat.
 “Ecophysiology and Biogeography of phototrophic consortia” (Prof. Dr. J. Overmann)
Institut für Mikrobiologie, Ludwig Maximilians Universität München
1999–2002 Doktorarbeit
Carl von Ossietzky Universität, Oldenburg und Ludwig Maximilians Universität, München
1999 Diplomarbeit,
“Isolierung und Charakterisierung von neuartigen phototrophen Purpurbakterien und ihre ökologische Relevanz” (Prof. Dr. J. Overmann)
Institut für Chemie und Biologie des Meeres, Universität Oldenburg, Paläomikrobiologie, Prof. H. Cypionka
1992–1999 Studium der Biologie
Carl von Ossietzky Universität, Oldenburg und University of Oregon, Eugene (USA)

Forschungsinteressen

Identifizierung neuartiger Antibiotika aus bisher nicht kultivierten und wenig untersuchten Bakterienphyla

Mikrobiologie

  • Mikrobielle Ökologie
  • Isolierung und Ökophysiologie von Mikroorganismen
  • Anaerobe Bakterien
  • Oxidativer Stress
  • Sekundärmetabolie und Antibiotika

Molekularbiologie

  • Mechanismen der Genregulatoin
  • Klonierung
  • Gentechnik
  • Genomik und Transkriptomik
  • Proteomik

Publikationen

Glaeser SP, Berghoff BA, Stratmann V, Grossart H-P, Glaeser J (2014) Contrasting effects of singlet oxygen and hydrogen peroxide on bacterial community composition in a humic lake. PLoS One, 9 (3) , 1–19.
Glaeser SP, Bolte K, Busse H-J, Kämpfer P, Grossart H-P, Glaeser J (2013) Novosphingobium aquaticum sp. nov. isolated from the humic matter rich Lake Grosse Fuchskuhle. International Journal of Systematic and Evolutionary Microbiology, 63 , 2630-2636.
Glaeser SP, Bolte K, Martin K, Busse H-J, Grossart H-P, Kämpfer P, Glaeser J (2013) Novosphingobium fuchskuhlense sp. nov. isolated from the north-east basin of Lake Grosse Fuchskuhle. International Journal of Systematic and Evolutionary Microbiology, 63 , 586-592.
Nuss AM, Adnan F, Weber L, Berghoff BA, Glaeser J, Klug G (2013) DegS and RseP homologous proteases are involved in singlet oxygen dependent activation of RpoE in Rhodobacter sphaeroides. PLoS One, 8 (11) , 1–15.
Berghoff BA, Glaeser J, Nuss AM, Zobawa M, Lottspeich F, Klug G (2011) Anoxygenic photosynthesis and photooxidative stress: a particular challenge for Roseobacter. Environmental Microbiology, 13 (3) , 775-791.
Berghoff BA, Glaeser J, Sharma C, Nuss AM, Zobawa M, Lottspeich F, Vogel J, Klug G (2011) Contribution of Hfq to photooxidative stress resistance and global regulation in Rhodobacter sphaeroides. Molecular Microbiology, 80 (6) , 1479-1495.
Glaeser J, Nuss AM, Berghoff BA, Klug G (2011) Singlet oxygen stress in microorganisms. Advances in Microbial Physiology, 58 , 141-173.
Peuser V, Glaeser J, Klug G (2011) The RSP_2889 gene product of Rhodobacter sphaeroides is a CueR homologue controlling copper-responsive genes. Microbiology, 157 , 3306-3313.
Glaeser SP, Grossart H-P, Glaeser J (2010) Singlet oxygen, a neglected but important environmental factor: Short-term and long-term effects on bacterioplankton composition in a humic lake. Environmental Microbiology, 12 (12) , 3124-3136.
Nuss AM, Glaeser J, Berghoff B, Klug G (2010) Overlapping alternative sigma factor regulons in the response to singlet oxygen in Rhodobacter sphaeroides. Journal of Bacteriology, 192 (10) , 2613-2623.
Berghoff BA, Glaeser J, Sharma C, Vogel J, Klug G (2009) Photooxidative stress induced and abundant small RNAs in Rhodobacter sphaeroides. Molecular Microbiology, 74 (6) , 1497-1512.
Glaeser SP, Kämpfer P, Busse H-J, Langer S, Glaeser J (2009) Proposal of Novosphingobium acidiphilum sp. nov., an acidophilic salt sensitive bacterium isolated from the humic acid rich Lake Grosse Fuchskuhle. International Journal of Systematic and Evolutionary Microbiology, 59 , 323-330.
Nuss AM, Glaeser J, Klug G (2009) RpoHII functions downstream of RpoE in the singlet oxygen dependent gene activation in Rhodobacter sphaeroides. Journal of Bacteriology, 191 (1) , 220-230.
Manske A-K, Henßge U, Glaeser J, Overmann J (2008) Subfossil 16S rRNA gene sequences of green sulfur bacteria in the Black Sea and implications for past photic zone anoxia. Applied and Environmental Microbiology, 74 (3) , 624-632.
Glaeser J, Zobawa M, Lottspeich F, Klug G (2007) Protein synthesis patterns reveal a complex regulatory response to singlet oxygen in Rhodobacter. Journal of Proteome Research, 6 (7) , 2460-2471.
Hendrischk A-K, Braatsch S, Glaeser J, Klug G (2007) The phrA gene of Rhodobacter sphaeroides encodes a photolyase and is regulated by singlet oxygen and peroxide in a σE-dependent manner. Microbiology, 153 , 1842-1851.
Vogl K, Glaeser J, Pfannes KR, Wanner G, Overmann J (2006) Chlorobium chlorochromatii sp. nov., a symbiotic green sulfur bacterium isolated from the phototrophic consortium "Chlorochromatium aggregatum". Archives of Microbiology, 185 (5) , 363-372.
Glaeser J, Klug G (2005) Photo-oxidative stress in Rhodobacter sphaeroides: protective role of carotenoids and expression of selected genes. Microbiology, 151 , 1927-1938.
Manske A-K, Glaeser J, Kuypers MMM, Overmann J (2005) Physiology and phylogeny of green sulfur bacteria forming a monospecific phototrophic assemblage at a depth of 100 meters in the Black Sea. Applied and Environmental Microbiology, 71 (12) , 8049-8060.
Glaeser J, Overmann J (2004) Biogeography, evolution, and diversity of epibionts in phototrophic consortia. Applied and Environmental Microbiology, 70 (8) , 4821-4830.
Glaeser J, Overmann J (2003) The significance of organic carbon compounds for in situ metabolism and chemotaxis of phototrophic consortia. Environmental Microbiology, 5 (11) , 1053-1063.
Glaeser J, Overmann J (2003) Characterization and in situ carbon metabolism of phototrophic consortia. Applied and Environmental Microbiology, 69 (7) , 3739-3750.
Glaeser J, Sterz M, Overmann, J (2003) Green sulfur bacteria in the chemocline. , in METEOR-Berichte 03-1, Ostatlantik-Mittelmeer-Schwarzes Meer, Cruise No. 51, Hemleben C, Hoernle K, Jørgensen BB, Roether W (Eds.) , 4-43 to 4-48. Leitstelle METEOR Institut für Meereskunde der Universität Hamburg:
Glaeser J, Bañeras L, Rütters H, Overmann J (2001) Novel bacteriochlorophyll e structures and species-specific variability of pigment composition in green sulfur bacteria Archives of Microbiology, 177 (6) , 476-485.
Glaeser J, Overmann J (1999) Selective enrichment and characterization of Roseospirillum parvum, gen. nov. and sp. nov., a new purple nonsulfur bacterium with unusual light absorption properties. Archives of Microbiology, 171 (6) , 405-416.
Tuschak C, Glaeser J, Overmann J (1999) Specific detection of green sulfur bacteria by in situ hybridization with a fluorescently labeled oligonucleotide probe Archives of Microbiology, 171 (4) , 265-272.